Trusted since 1908. Everyday fortified snacks. Optimal health biscuits. Essential vitamins & minerals. Glucosamine, antioxidants, fiber. Milk-Bone Essentials Plus Optimal Health Biscuits are tasty dog treats packed with essential vitamins & minerals to help support whole-dog health, plus antioxidants, glucosamine and fiber. Healthy Immune System: Antioxidants help support a healthy immune system. Hip, Joint & Bone Health: Glucosamine & calcium to help support joint and bone health. Digestive Health: With fiber to help support optimal digestive health. Milk-Bone Dog Snacks Heritage: We made our first biscuit over a century ago in a little bakery on the Lower East Side of New York City. We still use the same high quality and wholesome ingredients to make the original bone-shaped bone treat proving that after more than 100 years, it's still good to give. It's good to give. You're giving more than just a healthy & tasty treat. The makers of Milk-Bone dog snacks believe in giving back. That's why since 1997, a portion of every Milk-Bone dog snacks purchase goes towards providing service dogs to children and adults with physical disabilities and special needs. Visit MilkBone.com to see how you can help use change the lives of others in need. Calorie and fat content per biscuit: Milk-Bone Essential Plus Biscuits for Medium/Large Dogs: 39 calories per biscuit, 0.81 g fat per biscuit. Calorie content 3130 kcal/kg (calculated). This product is not intended to diagnose, cure or prevent any disease.